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Generic Name: Enalapril
Brand Name: Vasotec

Drug Class And Mechanism: Enalapril is a drug that is used for treating high blood pressure. It is in a class of drugs called angiotensin converting enzyme (ACE) inhibitors. ACE is an enzyme in the body that causes the formation of angiotensin II. Angiotensin II causes the arteries in the body to narrow, thereby elevating blood pressure. ACE inhibitors, such as enalapril, lower blood pressure by preventing the formation of angiotensin II thereby relaxing the arteries. ACE inhibitors also improve the effectiveness of the heart in patients with heart failure by reducing the blood pressure that the heart must maintain. Enalapril was approved by the FDA in December, 1985.

Prescribed For: Enalapril is used alone or in combination with other drugs to treat high blood pressure or congestive heart failure. After a heart attack, enalapril has been found to be effective in improving function of the damaged heart and in reducing symptoms and hospitalizations related to heart failure.

Dosing: The usual oral dose for treating high blood pressure is 2.5-40 mg once daily. It may also be administered twice daily. The dose for treating heart failure is 2.5-20 mg given twice daily. The usual intravenous dose is 1.25 mg every 6 hours.

Preparations: Tablets: 2.5, 5, 10, and 20 mg. Injection: 1.25 mg/mL STORAGE: Store below 30°C (86°F).

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